ISSN 0886-3067


Volume No 34 Issue No 1

Comparison of Anti-inflammatory Effect between Intracameral Triamcinolone Acetonide and Topical Dexamethasone after Phacoemulsification

Objective: To compare the role of single dose intracameral injection of triamcinolone acetonide versus topical dexamethasone to control post-operative inflammation after phacoemulsification. Study Design: Randomized controlled trial. Place and Duration of Study: Ophthalmology Department, Lahore General Hospital, Lahore, from March 2015 to August 2015. Methodology: A total of 60 patients of 40 70 years of age of either gender undergoing phacoemulsification for cataract were included. Selected patients were placed randomly into two groups by using lottery method. Group A patients were given 1 mg/0.1 ml triamcinolone acetonide into anterior chamber at the end of surgery and no topical steroids were given post-operatively. Group B were not given intracameral injection but topical dexamethasone eye drops were given 4 hourly for one week and then four times a day for 4 weeks. Outcome variable was control of post-operative inflammation, which was noted at day 1, 7 and 28. Results: Mean age of patients in group A was 58.63 7.30 years and in group B was 56.63 5.87 years. Out of 60 patients, 34 (56.67%) were males and 26 (43.33%) were females. The male to female ratio was 1.3:1. The difference in efficacy between the two groups was statistically non-significant. Conclusion: Single dose Intracameral injection of triamcinolone acetonide controls post-operative inflammation after phacoemulsification without the use of any eye drops and is equally as effective as topical dexamethasone for post-operative inflammation Keywords: Cataract, inflammation, Phacoemulsification, Triamcinolone.

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